The American Cancer Society’s Hope Lodge facilities have long offered cancer patients and their caregivers a free place to stay when their best hope for effective treatment may be in another city. Not having to worry about where to stay, or how to pay for lodging, allows guests to focus on getting better. Hope Lodge facilities have always provided a nurturing, home-like environment and this has been the driving design concept for the upcoming lodges in Dallas and Houston. The American Cancer Society and Perkins+Will partnered to create a home that provides an optimal healing environments by applying design strategies focused on optimal indoor air and water quality, nutrition, connections with nature and many additional strategies found within the WELL rating system. One of the top priorities included a dive into the building materials that would envelope the patient and their caregiver. To create optimal environments, these materials required the design teams evaluation for any substances with known health hazards – especially carcinogens. Throughout the project’s design, the spirit of partnership has allowed the team to work through the ups-and-down of new product trails and has created a supply of new knowledge that we would like to share with others wanting to do the same within their facilities. In our partnership we are working toward a day without cancer but we hope others will join in our efforts to drive market transformation where material health is a priority.